First slide

The world’s First PEGylated Bilirubin platform Technology

Bilix is established based on the world’s first PEGylated bilirubin platform technology to produce numerous “First in Class” and “Best in Class” anti-inflammatory and cancer therapy drugs in addition to achieving other business platform such as functional cosmeceutical, contrast agents for cancer diagnostics, and theranostics.

  • Founder & CEO Myung L. Kim, Ph.D
  • Professor SangYong Jon
Second slide

Bilirubin: Byproduct of heme metabolism

Developmental strategy

Target indication with BRNP

Acute inflammatory disease with IV or infusion treatment

  • Organ transplantation
  • Buerger’s disease
  • Ischemic heart disease
  • Ischemic stroke

Chronic inflammatory disease with SC or oral administration

  • Inflammatory bowl disease
  • Rheumatoid arthritis

Target indication with BRNP

Cancer drug carrier

  • Hepatocellular carcinoma with Nexavar @ BRNP
  • Cytotoxic cancer drugs: Doxorubicin, paxclitaxel

Peptide drug conjugated BRNP

Third slide

One Platform Target All with Pegylated bilirubin

We are the first to case a New Technology that Converted Bilirubin to a New Drug.

Fourth slide

OPTA Platform

fifth slide

3 Areas of PEGyated Bilirubin Applications

01Inflammation

02Cancer

03Imaging Contrast Agent

Patent #1
Bilirubin nanoparticle, use thereof, and preparation method therefor
[Filing Number: 10-2013-0165718(2013.12.27), KR, PCT, US, EP]
Patent #2
Engineering of various metal coordinated complexes with PEGylated bilirubin and its diverse application
[Filing Number: 10-2017-0059597(2017.05.12), KR, PCT, US, EP]
Patent #3
Bilirubin Derivatives Based Ultrasound Contrast Agent For Theranostics
[Filing Number: 10-2018-0014160, KR, PCT, US, EP]
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